5th Bench and Bed Immunology 2018
Systemic Lupus (SLE)
19th, 20th April, in Strasbourg
Locations:
Strasbourg University
Speakers / Chairs:
Prof. Dr. KORGANOW, Anne-Sophie, Strasbourg
Prof. Dr. VOLL, Reinhard, Freiburg
- Prof. Dr. ARNAUD, Laurent
- Prof. Dr. BLANCO, Patrick
- Dr. CHEVALIER, Nina
- Dr. GROS, Frédéric
- Dr. JUNG, Sophie
- Prof. Dr. LORENZ, Hannes
- Prof. Dr. MARTIN, Thierry
- Dr MARX, David
- Dr. MONNEAUX, Fanny
- Dr. NIETERS, Alexandra
- Dr. RIZZI, Marta
- Prof. Dr. SCHWARTING, Andreas
- Dr. SEHNERT, Bettina
- Prof. Dr. SOULAS-SPRAUEL, Pauline
- PD Dr. THIEL, Jens
- Dr. TRIANTAFYLLOPOULOU, Antigoni
- PD Dr. VENHOFF, Nils
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Program
FIRST DAY APRIL 19th, morning
9:30: Welcome and Coffee
9:45: Introduction (Reinhard Voll, Freiburg; Anne-Sophie Korganow, Strasbourg)
10:00-10:30: SLE, classification - diagnosis (Hannes Lorenz, Heidelberg)
10:30-11:10: SLE pathogenesis (Reinhard Voll, Freiburg)
11:10-11:30: COFFEE BREAK
11:30-12:00: SLE epidemiology (Laurent Arnaud, Strasbourg)
12:00-12:20: Kidney and SLE, new insights (David Marx; Thomas El Jammal, Strasbourg)
12:30-14:00: LUNCH
FIRST DAY APRIL 19th, afternoon
14:00-15:00: Workshop: Translational research in SLE/ Kidney, Skin (Sophie Jung, Strasbourg)
12 minutes for each talk (incl. questions):
• Maté Krauscz, Freiburg: ADA2 is a new member of nucleic acid sensors
• Mykolas Bendorius, Strasbourg: Neuropsychiatric lupus: autophagy and inflammation
• Aurore Meyer, Strasbourg: Neutrophils and SLE
• Delphine Bouis, Strasbourg: Targeting IFN pathway in SLE
• Natalie Frede, Freiburg: JAK inhibitors in SLE: from mouse models to clinical trials
15:00-15:15 BREAK
15:15-16:15: Workshop: Experimental models of SLE (Bettina Sehnert, Jens Thiel, Freiburg)
12 minutes for each talk (incl. questions):
• Lucie Aubergeon, Strasbourg: A novel human SLE model in humanized mice
• Alexandra Eichhorst, Freiburg: Influence of dietary fiber and short fatty-acids on SLE pathogens in 2 different SLE
models
• Romain Veber, Strasbourg: Lymphoid neogenesis in kidneys during lupus: involvement of CXCR3 expressing T cells
• Quentin Reuschlé, Strasbourg: ERN1 and autoimmunity
• Sophia Lecomte, Strasbourg: Characterization of the LN stromal compartment in BW mice
16:15-16:45: COFFEE BREAK
16:45-17:15: Epigenetics in SLE (Alexandra Nieters, Freiburg)
17:15-17:45: Predictors of fatigue and severe fatigue in a large multicenter and international cohort of patients with systemic lupus
erythematosus: the FATILUP study (The first completed LBBR study) (Thierry Martin, Strasbourg)
17:45-18:15: Targeted Therapy in SLE (Andreas Schwarting, Mainz)
18:15-19:30: Project discussion
19:45: DINNER
SECOND DAY 20th, morning
9:00-9:30: SLE genetics (Pauline Soulas Sprauel, Strasbourg)
9:30-10:00: B cells and SLE (Anne-Sophie Korganow, Strasbourg)
10:00-10:30 : T cells and SLE (Fanny Monneaux, Strasbourg)
10:30-10:50: COFFEE BREAK
10:50-11:20: Monogenetic models of autoimmunity: Autoimmune lymphoproliferative syndrome (Marta Rizzi, Freiburg)
11:20-12:00: Dendritic cells in SLE (Patrick Blanco, Bordeaux)
12:00-12:30: Innate immune cells in the pathogenesis of SLE (Antigoni Triantafyllopoulou Berlin/Freiburg)
12:30-14:00: LUNCH
SECOND DAY 20th, afternoon
14:00-15:00: Workshop: Autoantibodies-B cells in SLE (Nils Venhoff, Freiburg)
12 minutes for each talk (including questions):
• Raquel Lorenzetti, Freiburg: CTLA4 Ig treatment induces modulation of B cell function and differentiation
• Yannick Dieudonné, Strasbourg: Impaired TLR9 reponses in B cells from patients with SLE
• Mélanie Sieder: B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity
• Erika Palacios, Strasbourg: Lupus light project.
• Sonia Heistand, Freiburg: SLE and Rituximab
15:00-15:15: BREAK
15:15-16:15 Workshop: T cells in SLE (Nina Chevalier, Freiburg)
12 minutes for each talk (including questions):
• Philippe Mertz, Strasbourg: T cell lymphopenia and SLE
• Arianna Troilo, Freiburg: Th17 and Th1 cells in SLE
• Adam Klocperk, Freiburg: A novel NOD2/IFNg R2 mutation presenting with infection and autoinflammation
• Cerise Guillochon-Petitcuenot, Strasbourg The role of dietary sodium intake on the modulation of Th17 and Tregs
16:15-16:45 COFFEE BREAK
16:45-17:15: Life and death in SLE (Frédéric Gros, Strasbourg)
17:15-18:30: Discussion around coffee (Thierry Martin and Reinhard Voll)
18:30: END OF BBI 2018