Our Research Projects
Research area: Hematopoiesis and Development
1. Mechanobiology of the blood-bone marrow barrier and impact on platelet formation
Supervisor: Dr. Nathalie Brouard/Dr. Catherine Léon
PhD Fellow: Faten Tlili
Institution: University of Strasbourg (FR)
2. Role of Ikaros in the development of Th17 lymphocytes
Supervisor: Dr. Susan Chan/Dr. Céline Charvet
PhD Fellow: Caroline Targino
Institution: University of Strasbourg (FR)
3. Stroma – plasma cell interaction as driver of antibody-mediated autoimmune disease
Supervisor: Prof. Dr. Reinhard Voll
PhD Fellow: Paola Fernanda Ruiz Aparicio
Institution: University Medical Center Freiburg (DE)
4. Drug targeting of mesenchymal - hematopoietic cell interaction
Supervisor: Dr. Christopher Mueller
PhD Fellow: Guillermo Federico Perez
Institution: University of Strasbourg (FR)
5. 3D model of olfactory mucosa immune defense against SARS-Cov2 infection
Supervisor: Dr. Vincent Flacher
PhD Fellow: Annia Pérez Riverón
Institution: University of Srasbourg (FR)
6. Investigating macrophage populations regarding cytomegalovirus infection
Supervisor: Prof. Dr. Philipp Henneke
PhD Fellow: Agnibesh Dey
Institution: University Medical Center Freiburg (DE)
7. Role of the Ikaros family proteins in embryonic blood cell development
Supervisor: Dr. Susan Chan
PhD Fellow: Mahassen El Khoury
Institution: University of Strasbourg (FR)
Research area: Innate and Adaptive Effector Functions
8. Regulation of the immune response by the spleen
Supervisor: Dr. Blandine Maitre
PhD Fellow: Gabriel Rojas Jiménez
Institution: University of Strasbourg (FR)
9. Post translational modifications of IL-1β; regulation and roles in IL-1β activation
Supervisor: Prof. Dr. Georg Häcker
PhD Fellow: Danielle Paige Anthony
Institution: University Medical Center Freiburg (DE)
10. Modulating T cell signaling for improved anti-tumor responses
Supervisor: Prof. Dr. Björn Lillemeier
PhD Fellow: Vasileios Morfos
Institution: University of Freiburg (DE)
11. Dysregulation of B cell function in ANCA associated vasculitis
Supervisor: Prof. Dr. Marta Rizzi
PhD Fellow: Bruno Benassini
Institution: University Medical Center Freiburg (DE)
12. NLRP proteins in health and disease
Supervisor: Prof. Dr. Olaf Groß
PhD Fellow: Xipeng Wang
Institution: University Medical Hospital Freiburg (DE)
13. Monitoring affinity maturation during chronic viral infection
Supervisor: Prof. Dr. Daniel Pinschewer
PhD Fellow: Cemre Seven
Institution: University of Basel (CH)
14. Impact of macrophages signaling and metabolism on NLRP3 inflammasome activity
Supervisor: Prof. Dr. Olaf Groß
PhD Fellow: Clara Dufossez
Institution: University Medical Hospital Freiburg (DE)
15. Crosstalk between lymphatic endothelial cells in lymphoid organs
Supervisor: Dr. Christopher Mueller
PhD Fellow: Shadrack Owusu
Institution: University of Strasbourg (FR)
16. Investigating the presence and role of MR1-restricted T cells in Inflammatory Bowel Disease (IBD)
Supervisor: Prof. Dr. Petr Hruz
PhD Fellow: Vanshika Rastogi
Institution : University of Basel (CH)
17. The physiology of MR1T cells in tumors and their use in cell therapy
Supervisor: Prof. Dr. Gennaro De Libero
PhD Fellow: Natalie Kehrer
Institution: University of Basel (CH)
Research area: Immune-related Diseases
18. Functional analysis of genetic variants in patients with inborn errors in T cells or B cells: monogenetic defects in transcription factors in late-onset hypogammaglobulinemia
Supervisor: Prof. Dr. Bodo Grimbacher
PhD Fellow: Aishwarya Saxena
Institution: University Medical Center Freiburg (DE)
19. Modified TCRs on human T cells targeting tumor cells
Supervisor: Prof. Dr. Wolfgang Schamel
PhD Fellow: Trang Nguyen
Institution: University of Freiburg (DE)
20. Deciphering resistance mechanisms in cancer immunotherapy
Supervisor: Prof. Dr. Alfred Zippelius
PhD Fellow: Irene Fusi
Institution: University of Basel (CH)
21. Contribution of CD44 expressed on tumour-associated macrophages (TAMs) to progression of pancreatic cancer
Supervisor: Prof. Dr. Véronique Orian-Rousseau
PhD Fellow: Nagwa Ibrahim
Institution: Karlsruhe Institute of Technology (DE)
22. Identification of novel therapeutic targets in oncogenic signaling pathways in mastocytosis
Supervisor: Prof. Dr. Karin Hartmann
PhD Fellow: Alina Makeeva
Institution: University of Basel (CH)
23. Lymphoid stromal cells in common variable immunodeficiency : potential orchestrators of the altered humoral response?
Supervisor: Prof. Dr. Klaus Warnatz
PhD Fellow: Victoria Cousin
Institution: University Medical Center Freiburg (DE)
24. B cell heterogeneity during tuberculosis infection
Supervisor: Prof. Dr. Carolyn King
PhD Fellow: Wadschma Naderi
Institution: University of Basel (CH)
25. Determining the prevalence of binding epitopes for autoantibodies in the human population
Supervisor: Prof. Dr. Frank Breitling
PhD Fellow: Karen Cárdenas Casillas
Institution: Karlsruhe Institute of Technology (DE)
26. Heterogeneity of virus specific CD8+ T cell dysfunction in HIV infection
Supervisor: Prof. Dr. Robert Thimme
PhD Fellow: Wasihun Hailemichael
Institution: University Medical Center Freiburg (DE)
27. Structural and functional characterization of human cytomegalovirus (HCMV) Fcγ binding glycoprotein interaction with B cells
Supervisor: Prof. Dr. Hartmut Hengel
PhD Fellow: Haneen Daralnakhla
Institution: University Medical Center Freiburg (DE)